Dr. Prasanna Karki
Consultant
Dr. Prasanna Karki is a Consultant Neurointerventional Neurosurgeon at Nepal Mediciti, specializing in advanced, minimally invasive treatments for complex neurovascular diseases. With extensive expertise in managing acute ischemic stroke, cerebral aneurysms, carotid artery stenosis, and arteriovenous malformations (AVMs), Dr. Karki employs cutting-edge interventional techniques that reduce patient pain, lower procedural risks, and promote faster recovery compared to traditional neurosurgical methods.
Her specialized treatments significantly benefit patients suffering from brain trauma, brain tumors, hydrocephalus, and pediatric brain tumors, offering innovative solutions for challenging neurological conditions.
Dr. Karki completed her MBBS at Nepal Medical College and Teaching Hospital in 2009 and earned her MD and Ph.D. in Neurosurgery from the prestigious Graduate School of Medical and Dental Sciences at Kagoshima University Hospital, Japan, in 2015. She has held key positions as a Consultant Neurosurgeon and Lecturer at Annapurna Neurological Hospital and Nepalgunj Medical College, and Teaching Hospital.
After four successful years at Nepal Mediciti Hospital, she further enhanced her expertise through a specialized Clinical Fellowship in Neurointerventional Surgery at Siriraj Hospital, Mahidol University, Thailand.
Dr. Karki has contributed significantly to neurosurgical research, with 27 peer-reviewed publications in national and international journals, reflecting her dedication to advancing neurosurgery through innovative, minimally invasive techniques that improve patient outcomes and quality of life.
Education
Area of Focus
- Neurosurgery
- Neurointervention
Language spoken
- ENGLISH
- NEPALI
- HINDI
- JAPANESE
Fellowship in Neurointervention 2022- Siriraj Hospital (Mahidol University)
Cadaver dissection course on skull base and vascular surgery, Kyorin University, Tokyo, Japan- 2011, 2012, 2013, 2015
Cadaver dissection course on skull base and spinal surgery, Hiroshima University, Hiroshima, Japan-2013 and 2014
Various micro neurosurgery training courses, Kagoshima University, Kagoshima, Japan
Rhoton micro neurosurgery seminar, Fukuoka University, Fukuoka, Japan- 2010 and 2013
World Federation of Neurosurgical Societies (WFNS) Educational Courses in Dhaka, Bangladesh- 2012
LINNC Asia 2018, Singapore- Live course on Neurointerventional Techniques
WLNC Barcelona 2019- Live course on Neurointerventional Techniques
LINNC Asia 2019, Singapore- Live course on Neurointerventional Techniques
ACNS 2019, Nepal – Hands-on course on Neurointerventional Techniques
Juntendo University -Tokyo, Japan 2021-2022- Virtual Endovascular training 3.5 Months
LINNC Asia 2022, Singapore- Live course on Neurointerventional Techniques
Interventional neurosurgery, Functional and Stereotactic Neurosurgery, Pediatric Neurosurgery
Original articles
S Joshi, P Paudel, P Karki, DB Shah, GR Sharma. Ex vivo preservation technique of autologous bone flap in resource-limited settings: Retrospective analysis of outcome based on a single institute in Nepal. Nepal Journal of Neuroscience. Vol. 19 No. 1 (2022) Feb
Karki, P., Sharma, G., Joshi, S., Poudel, P., Shah, D. (2021). Microvascular Decompression using muscle graft for interposition: A retrospective study
https://doi.org/10.3126/njn.v18i2.36673
Karki, P., Sharma, G., Joshi, S., Poudel, P., Shah, D. (2021). Retrospective study and outcome predictor after microsurgical resection of cerebral arteriovenous malformations in Nepal. Asian Journal of Neurosurgery. 10.4103/ajns.AJNS_509_20
Shah, D., Sharma, G., Joshi, S., Poudel, P., Karki, P. 2021). Outcome of decompressive craniectomy for traumatic brain injury: An institutional-based analysis from Nepal. Asian Journal of Neurosurgery. 10.4103/ajns.AJNS_392_20
Sharma G, Poudel P, Joshi S, Shah D, Karki P. Risk factors and outcome analysis of patients with intraoperative rupture (IOR) of ruptured cerebral aneurysm during microsurgical clipping. British Journal of Neurosurgery. (Ahead of print)
Clinical Outcome and Recurrence After Meningioma Surgery: An Experience from a Developing Country, Nepal. Sharma Gopal Raman, Paudel Prakash, Joshi Sumit, Shah Damber Bikram, Karki Prasanna
Analysis of risk factors for prolonged hospitalization in chronic Subdural hematoma undergoing single burr hole and drainage. Sumit Joshi, Prakash Paudel, Damber Bikram Shah, Prasanna Karki, Gopal Raman Sharma
Paudel, P., Shah, D., Joshi, S., Karki, P., Budhathoki, S., & Sharma, G. (2020). Patient Reported Outcome Analysis after Posterior Decompression and Posterolateral Fusion Surgery in Lumbar Degenerative Spondylolisthesis. Nepal Journal of Neuroscience, 17(2), 35-41. https://doi.org/10.3126/njn.v17i2.30498
Karki P, Yamagami M, Takasaki K, et al. Microvascular decompression in patients 30 years old or younger. Asian Journal of Neurosurgery. 2018 Feb 8 Accepted
Karki P, Kurihara T, Nakamachi T, et al. Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40. Molecular Pain. 2015 Jan 26
Case reports
Upadhyaya P, Karki P, Pokharel B, Sharma GR. Bilateral Internal Carotid Arteries Occlusion: A Case Report. JNMA J Nepal Med Assoc. 2022 Feb 15;60(246):207-210. doi: 10.31729/jnma.6877. PMID: 35210642; PMCID: PMC9200002
Karki, P., Shah, D., Joshi, S., Poudel, P., Kayastha, J., & Sharma, G. (2020). Microvascular Decompression using Muscle Graft for Vertebral Artery Medullary Compression Syndrome. Nepal Journal of Neuroscience, 17(3), 55-58. https://doi.org/10.3126/njn.v17i3.33128
Shah, D., Karki, P., Poudel, P., Joshi, S., Upadhhya, P., & Sharma, G. (2020). Lymphoplasmacyte-rich meningioma: a rare variant of meningioma mimicking diffuse granulomatous disease with leptomeningeal spread. Nepal Journal of Neuroscience, 17(3), 36-40. https://doi.org/10.3126/njn.v17i3.33123
Karki, P., Aryal, S., Aryal, G.,et al. (2019). Colloid cyst of the third ventricle: Histopathological and ultrastructural study. Journal of Pathology of Nepal, 9(2), 1590-1594. https://doi.org/10.3126/jpn.v9i2.24882, 2019 Sept Accepted
Bohara M, Karki P, Acharya S. Pediatric low-grade chondrosarcoma of upper cervical spine. Nepal Journal of Neuroscience 14: 49-50, 2017
Bohara M, Karki P, Chaudhary L, Pant B. Central Hyperthermia Treated with Baclofen in a Patient with Epidural Hematoma. Nepal Journal of Neuroscience. 2016 Nov. Accepted.
Karki P, Hirano H, Yamahata H, et al. Solitary Cranial Langerhans Cell Histiocytosis: Two Case Reports. Hiroshima J Med Sci. 2015 Dec 64(4): 59-63
Bohara M, Sugata S, Nishimuta Y, Karki P, Nagayama T, Sakamoto S, Tokimura H, Arita K. Effect of Revascularization on Headache Associated with Moyamoya Disease in Pediatric Patients. Hiroshima J Med Sci. 2015 Sep 64 (3): 39-44
Bohara M, Hirabaru M, Fujio S, Higashi M, Yonezawa H, Karki P, Hanaya R, Hirano H, Tokimura H, Arita K. Choroid Plexus Tumors: Experience of 10 Cases with Special References to Adult Cases. Neurol Med Chir (Tokyo). 2015 Oct 16. [Epub ahead of print]
Karki P, Bohara M, K Arita. An unusual tumor of the cerebellopontine angle. Nepal Journal of Neuroscience. 2015 Feb 25
Awa R, Campos F, Arita K, Sugiyama K, Tominaga A, Kurisu K, Yamasaki F, Karki P, Tokimura H, Fukukura Y, Fujii Y, Hanaya R, Oyoshi T, Hirano H. Neuroimaging diagnosis of pineal region tumors-quest for pathognomonic finding of germinoma. Neuroradiology. 2014 Jul;56(7):525-34
Karki P, Yonezawa H, et al. Third ventricular atypical meningioma, which recurred with further malignant progression. Brain Tumor Pathol. 2015 Jan;32(1):56-60
Yunoue S, Tokimura H, Tominaga A, Fujio S, Karki P, Usui S, Kinoshita Y, Habu M, Moinuddin FM, Hirano H, Arita K. Transsphenoidal surgical treatment of pituitary adenomas in patients aged 80 years or older. Neurosurg Rev. 2014 Apr;37(2):269-76
Bohara M, Karki P, Arika K. Pituitary hyperplasia due to primary hypothyroidism mimicking adenoma. Nepal Journal of Neuroscience 2013; 10:79-80.
Bohara M, Yonezawa H, Karki P, Bakhtiar Y, Hirano H, Kitazono I, Matsuyama N, Arita K. Mature posterior fossa teratoma mimicking dermoid cyst. Brain Tumor Pathol 2012 Dec 23. [Epub ahead of print]
Yamahata H, Yunoue S, Tokimura H, Hanaya R, Hirano H, Tokudome M, Karki P, Yonezawa H, Sugata S, Kawahara K, Maruyama I, Arita K. Immunohistochemical expression of thrombomodulin in vestibular schwannoma. Brain Tumor Pathol 2013 Jan;30(1):28-33
Karki P, Bohara M, Yonezawa H, Tokimura H, Hirano H, Hanaya R, Arita K. Cerebellopontine angle endodermal cyst presenting with hemifacial spasm. Brain Tumor Pathol 2011 Oct;28(4):371-4
2022 Nov: “Young practitioners grant” to attend LINNC neurointervention seminar 2019, Singapore
2020 Nov: 2nd Runner-up of the Young Neurosurgeons’ Award by the World Federation of Neurological Surgeons and Asian Congress of Neurological Surgeons
2019 Nov: “Young practitioners grant” to attend LINNC neurointervention seminar 2019, Singapore
2018 Nov: “Young practitioners grant” to attend LINNC neurointervention seminar 2018, Singapore
2017 Apr: Felicitation by Otsuka Toshimi Foundation on its 10th anniversary for contribution to the neuroscience of Nepal, Tokushima, Japan
2014 Jan: “Excellent medical research presentation award” for the research paper presented at Kagoshima University, Japan
2013 Apr: “Japanese government (Monbukagakusho) Scholarship” for research and postgraduate doctoral study in neurosurgery in Japan
2012 Apr: Otsuka Toshimi Foundation Scholarship for research and postgraduate doctoral study in Neurosurgery in Japan
2011 Apr: Otsuka Toshimi Foundation Scholarship for research and postgraduate doctoral study in Neurosurgery in Japan
Member of Nepalese Society of Neurosurgeons (NESON)
Member of Nepal Medical Association (NMA)
Congress of Neurological Surgeons (CNS)
Member of the Japan Neurosurgical Society (JNS)
Member of the European Association of Neurosurgical Societies (EANS)
Sectional membership of Functional Neurosurgery (EANS)
