Dr. Prasanna Karki
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Dr. Prasanna Karki

Consultant


Dr. Prasanna Karki is a Consultant Neurointerventional Neurosurgeon at Nepal Mediciti, specializing in advanced, minimally invasive treatments for complex neurovascular diseases. With extensive expertise in managing acute ischemic stroke, cerebral aneurysms, carotid artery stenosis, and arteriovenous malformations (AVMs), Dr. Karki employs cutting-edge interventional techniques that reduce patient pain, lower procedural risks, and promote faster recovery compared to traditional neurosurgical methods.

Her specialized treatments significantly benefit patients suffering from brain trauma, brain tumors, hydrocephalus, and pediatric brain tumors, offering innovative solutions for challenging neurological conditions.

Dr. Karki completed her MBBS at Nepal Medical College and Teaching Hospital in 2009 and earned her MD and Ph.D. in Neurosurgery from the prestigious Graduate School of Medical and Dental Sciences at Kagoshima University Hospital, Japan, in 2015. She has held key positions as a Consultant Neurosurgeon and Lecturer at Annapurna Neurological Hospital and Nepalgunj Medical College, and Teaching Hospital.

After four successful years at Nepal Mediciti Hospital, she further enhanced her expertise through a specialized Clinical Fellowship in Neurointerventional Surgery at Siriraj Hospital, Mahidol University, Thailand.

Dr. Karki has contributed significantly to neurosurgical research, with 27 peer-reviewed publications in national and international journals, reflecting her dedication to advancing neurosurgery through innovative, minimally invasive techniques that improve patient outcomes and quality of life.


Education

Area of Focus

  • Neurosurgery
  • Neurointervention

Language spoken

  • ENGLISH
  • NEPALI
  • HINDI
  • JAPANESE

  • Fellowship in Neurointervention 2022- Siriraj Hospital (Mahidol University)
  • Cadaver dissection course on skull base and vascular surgery, Kyorin University, Tokyo, Japan- 2011, 2012, 2013, 2015
  • Cadaver dissection course on skull base and spinal surgery, Hiroshima University, Hiroshima, Japan-2013 and 2014
  • Various micro neurosurgery training courses, Kagoshima University, Kagoshima, Japan
  • Rhoton micro neurosurgery seminar, Fukuoka University, Fukuoka, Japan- 2010 and 2013
  • World Federation of Neurosurgical Societies (WFNS) Educational Courses in Dhaka, Bangladesh- 2012
  • LINNC Asia 2018, Singapore- Live course on Neurointerventional Techniques
  • WLNC Barcelona 2019- Live course on Neurointerventional Techniques
  • LINNC Asia 2019, Singapore- Live course on Neurointerventional Techniques
  • ACNS 2019, Nepal – Hands-on course on Neurointerventional Techniques
  • Juntendo University -Tokyo, Japan 2021-2022- Virtual Endovascular training 3.5 Months
  • LINNC Asia 2022, Singapore- Live course on Neurointerventional Techniques

Interventional neurosurgery, Functional and Stereotactic Neurosurgery, Pediatric Neurosurgery

Scientific Publications

Original articles

  1. S Joshi, P Paudel, P Karki, DB  Shah, GR Sharma. Ex-vivo preservation technique of autologous bone flap in resource limited settings: Retrospective analysis of outcome based on single institute of Nepal.  Nepal Journal of Neuroscience. Vol. 19 No. 1 (2022) Feb.
  2. Karki, P., Sharma, G., Joshi, S., Poudel, P., Shah, D.,(2021). Microvascular Decompression using muscle graft for interposition: A retrospective study

https://doi.org/10.3126/njn.v18i2.36673

  1. Karki, P., Sharma, G., Joshi, S., Poudel, P., Shah, D.,(2021). Retrospective study and outcome predictor after microsurgical resection of cerebral arteriovenous malformations in Nepal. Asian Journal of Neurosurgery. 10.4103/ajns.AJNS_509_20
  2. Shah, D., Sharma, G., Joshi, S., Poudel, P., Karki, P. 2021). Outcome of decompressive craniectomy for traumatic brain injury: An institutional-based analysis from Nepal. Asian Journal of Neurosurgery. 10.4103/ajns.AJNS_392_20
  3. Sharma G, Poudel P, Joshi S, Shah D, Karki P. Risk factors and outcome analysis of patients with intraoperative rupture (IOR) of ruptured cerebral aneurysm during microsurgical clipping. British Journal of Neurosurgery. (Ahead of print)
  4. Clinical Outcome and Recurrence After Meningioma Surgery: An Experience from a Developing Country, Nepal. Sharma Gopal RamanPaudel PrakashJoshi SumitShah Damber BikramKarki Prasanna
  5. Analysis of risk factor for prolong hospitalization in chronic Subdural hematoma undergoing single burr hole and drainage. Sumit Joshi, Prakash Paudel, Damber Bikram Shah, Prasanna Karki, Gopal Raman sharma
  6. Paudel, P., Shah, D., Joshi, S., Karki, P., Budhathoki, S., & Sharma, G. (2020). Patient Reported Outcome Analysis after Posterior Decompression and Posterolateral Fusion Surgery in Lumbar Degenerative Spondylolisthesis. Nepal Journal of Neuroscience17(2), 35-41. https://doi.org/10.3126/njn.v17i2.30498
  7. Karki P, Yamagami M, Takasaki K, et al. Microvascular decompression in patients 30 years old or younger. Asian Journal of Neurosurgery. 2018 Feb 8 Accepted.
  8. Karki P, Kurihara T, Nakamachi T, et al. Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40. Molecular Pain. 2015 Jan 26.

 

Case reports

  1. Upadhyaya P, Karki P, Pokharel B, Sharma GR. Bilateral Internal Carotid Arteries Occlusion: A Case Report. JNMA J Nepal Med Assoc. 2022 Feb 15;60(246):207-210. doi: 10.31729/jnma.6877. PMID: 35210642; PMCID: PMC9200002.
  2. Karki, P., Shah, D., Joshi, S., Poudel, P., Kayastha, J., & Sharma, G. (2020). Microvascular Decompression using Muscle Graft for Vertebral Artery Medullary Compression Syndrome. Nepal Journal of Neuroscience17(3), 55-58. https://doi.org/10.3126/njn.v17i3.33128
  3. Shah, D., Karki, P., Poudel, P., Joshi, S., Upadhhya, P., & Sharma, G. (2020). Lymphoplasmacyte rich meningioma: a rare variant of meningioma mimicking diffuse granulomatous disease with leptomeningeal spread. Nepal Journal of Neuroscience17(3), 36-40. https://doi.org/10.3126/njn.v17i3.33123
  4. Karki, P., Aryal, S., Aryal, G.,et al. (2019). Colloid cyst of third ventricle: Histopathological and ultrastructural study. Journal of Pathology of Nepal9(2), 1590-1594. https://doi.org/10.3126/jpn.v9i2.24882, 2019 Sept Accepted.
  5. Bohara M, Karki P, Acharya S. Pediatric low-grade chondrosarcoma of upper cervical spine. Nepal Journal of Neuroscience 14: 49-50, 2017.
  6. Bohara M, Karki P, Chaudhary L, Pant B. Central Hyperthermia Treated with Baclofen in a Patient with Epidural Hematoma. Nepal Journal of Neuroscience. 2016 Nov. Accepted.
  7. Karki P, Hirano H, Yamahata H, et al. Solitary Cranial Langerhans Cell Histiocytosis: Two Case Reports. Hiroshima J Med Sci. 2015 Dec 64(4): 59-63.
  8. Bohara M, Sugata S, Nishimuta Y, Karki P, Nagayama T, Sakamoto S, Tokimura H, Arita K. Effect of Revascularization on Headache Associated with Moyamoya Disease in Pediatric Patients. Hiroshima J Med Sci. 2015 Sep 64 (3): 39-44.
  9. Bohara M, Hirabaru M, Fujio S, Higashi M, Yonezawa H, Karki P, Hanaya R, Hirano H, Tokimura H, Arita K. Choroid Plexus Tumors: Experience of 10 Cases with Special References to Adult Cases. Neurol Med Chir (Tokyo). 2015 Oct 16. [Epub ahead of print].
  10. Karki P, Bohara M, K Arita.  An unusual tumor of the cerebellopontine angle. Nepal Journal of Neuroscience. 2015 Feb 25.
  11. Awa R, Campos F, Arita K, Sugiyama K, Tominaga A, Kurisu K, Yamasaki F, Karki P, Tokimura H, Fukukura Y, Fujii Y, Hanaya R, Oyoshi T, Hirano H. Neuroimaging diagnosis of pineal region tumors-quest for pathognomonic finding of germinoma. Neuroradiology. 2014 Jul;56(7):525-34.
  12. Karki P, Yonezawa H, et al. Third ventricular atypical meningioma which recurred with further malignant progression. Brain Tumor Pathol. 2015 Jan;32(1):56-60.
  13. Yunoue S, Tokimura H, Tominaga A, Fujio S, Karki P, Usui S, Kinoshita Y, Habu M, Moinuddin FM, Hirano H, Arita K. Transsphenoidal surgical treatment of pituitary adenomas in patients aged 80 years or older. Neurosurg Rev. 2014 Apr;37(2):269-76
  14. Bohara M, Karki P, Arika K. Pituitary hyperplasia due to primary hypothyroidism mimicking adenoma. Nepal Journal of Neuroscience 2013; 10:79-80.
  15. Bohara M, Yonezawa H, Karki P, Bakhtiar Y, Hirano H, Kitazono I, Matsuyama N, Arita K. Mature posterior fossa teratoma mimicking dermoid cyst. Brain Tumor Pathol 2012 Dec 23. [Epub ahead of print]
  16. Yamahata HYunoue STokimura HHanaya RHirano HTokudome MKarki PYonezawa HSugata SKawahara KMaruyama IArita K. Immunohistochemical expression of thrombomodulin in vestibular schwannoma. Brain Tumor Pathol 2013 Jan;30(1):28-33.
  17. Karki P, Bohara M, Yonezawa H, Tokimura H, Hirano H, Hanaya R, Arita K. Cerebellopontine angle endodermal cyst presenting with hemifacial spasm. Brain Tumor Pathol 2011 Oct;28(4):371-4.

 

2022 Dec:        Fellowship in Neurointerventional Radiology from Siriraj Hospital, Mahidol University, Bangkok,                           Thailand

2022 Feb:        Virtual training (3.5 months) in Endovascular surgery – Juntendo University, Tokyo, Japan

2022 Nov:        “Young practitioners grant” to attend LINNC neurointervention seminar 2019, Singapore

2020 Nov:        2nd Runner up of Young Neurosurgeon’s Award by World Federation of Neurological Surgeons                           and Asian Congress of Neurological Surgeons

2019 Nov:        “Young practitioners grant” to attend LINNC neurointervention seminar 2019, Singapore

2018 Nov:        “Young practitioners grant” to attend LINNC neurointervention seminar 2018, Singapore

2017 Apr:         Felicitation by Otsuka Toshimi Foundation on its 10th anniversary for contribution in the                                        neuroscience of Nepal, Tokushima, Japan

2014 Jan:        “Excellent medical research presentation award” for the research paper  presented at                                            Kagoshima University, Japan

2013 Apr:        “Japanese government (Monbukagakusho) Scholarship” for research  and postgraduate doctoral                         study in neurosurgery in Japan

2012 Apr:        Otsuka Toshimi Foundation Scholarship for research and postgraduate doctoral study in                                      Neurosurgery in Japan

2011 Apr:        Otsuka Toshimi Foundation Scholarship for research and postgraduate doctoral study in                                      Neurosurgery in Japan

Nepal Medical Council (NMC); Medical Practitioner No: 8790 

                           (Specialist certification in Neurosurgery- 2015)

                        (Specialist certification in Neurointerventional Surgery- 2022)

 

  • Nepalese Society of Neurosurgeons (NESON)
  • Nepal Medical Association (NMA)
  • Congress of Neurological Surgeons (CNS)
  • Japan Neurosurgical Society (JNS)
  • The European Association of Neurosurgical Societies (EANS)
  • Sectional membership of Functional Neurosurgery (EANS)

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